It may sound counterintuitive to recommend Western medicine for a condition known as hypothyroxinemia, but it’s not a matter of medical opinion.
That is, patients who are treated with the medications are unlikely to develop thyroid dysfunction or any other health problems.
Instead, patients are encouraged to take them as prescribed, said Dr. Michael E. Pacheco, chairman of the department of medicine and psychiatry at the University of Pittsburgh Medical Center and a professor of medicine.
The medications are available in three forms: the oral form, a cream that is applied to the face and neck and worn around the neck, and a pill.
Both are taken by mouth and are taken in a pill form.
Both medications contain a protein that binds to thyroid hormone and prevents it from reaching the thyroid gland.
They also can lower blood pressure, improve cholesterol levels, and reduce the amount of thyroid hormone that is stored in the body.
But for patients who cannot take the medications or don’t want to take the pills, there are other options available.
Western medicine is an effective treatment for people with hypothyrogenesis, but a number of clinical trials have found that it doesn’t work for most patients.
A 2010 review of the literature found that most of the studies were done with people who already had a medical condition that caused hyperthyroidism, such as a genetic disease, or a substance known as beta-blockers.
A study published last year in the journal BMJ Open compared the effectiveness of two common forms of treatment, called tricyclic antidepressants and hypothyroglutamic acid, or HGA, for patients with hypo thyroidism, or mild hypothyrosinemia.
Those who took the drugs had a significantly lower risk of developing hypothyroids and a significantly higher risk of death than people who took no medications.
“There’s a huge body of evidence showing that people with mild hypo-thyroid disease have a much lower risk than people with normal hypothyrogens,” said Dr, James P. Gee, a professor at the Mayo Clinic in Rochester, Minnesota, who was not involved in the review.
A 2011 study published in the Journal of the American Medical Association found that patients taking HGA had a nearly threefold higher risk for developing hypoothyroid conditions than patients who took a placebo.
Another review published in May 2017 in The Journal of Clinical Endocrinology & Metabolism looked at more than 400 patients who were treated with two types of anti-thyrotic drugs — oral or depot — in the US for a range of conditions.
Those patients had significantly lower odds of developing symptoms of hypothyrosis and hyperthyrosis than those who received a placebo, and the odds of having an underlying disease that was not treated with HGA were nearly three times higher.
In a second study published earlier this year, the same researchers found that the medications had a greater effect on people with chronic obstructive pulmonary disease, a condition in which chronic lung disease has worsened over time.
The drugs had no effect on the other side of the spectrum, which is hyperthyrotics, a class of patients whose underlying disease is not treated and can lead to fatigue, joint pain, and even heart problems.
Some doctors argue that people who take the drugs should not be discouraged from taking them, because many of the drugs work well in patients who have no underlying condition.
“I don’t think it’s necessary to be worried about how they’re going to treat patients with mild hyperthyrogenesis,” said Daniel A. T. Boulton, a neurologist at the Yale School of Medicine and co-author of a study published this year in Nature Medicine.
“If a patient is having some symptoms that are just not normal, they can take the medication and have the normal symptoms.”
A 2015 Cochrane review found that some medications were effective in treating mild hypothyroidism.
But the authors said the results were mixed, with some studies showing a greater benefit for the drugs than others.
“Overall, the literature is not very supportive of the idea that these medications are effective in mild hypotyroid patients,” said co-authors Dr. David A. B. Wijnenkamp, an endocrinologist at the Children’s Hospital of Philadelphia and a researcher at the Institute of Psychiatry at the London School of Hygiene & Tropical Medicine.
They concluded that the data is more limited, and there are many factors that may explain the findings, including whether the patients were taking other medications and whether they were taking a medication that didn’t cause the same symptoms.
Some of the medications have also been associated with serious side effects, including blood clots and heart problems, and some patients have died because of side effects.
But some doctors are wary of prescribing the drugs, even though they are effective for people who don’t have the underlying conditions.
“We don’t know enough to recommend them,” said Professor Gee. “What